Oral Florid Papillomatosis Associated with Malignant Acanthosis Nigricans – a Case Report with a Review of the Literature

Oral florid papillomatosis is best defined as a type of verrucous carcinoma with local invasion and minimal dysplasia as well as a low incidence of metastases.Human papilloma virus infection is considered to trigger and perpetuate the disease, hence, its role in the the pathogenesis of the oncogenic process is still obscured.Herein, a very anecdotal case of HPV-driven oral florid papillomatosis in association with some clinical features of malignant acanthosisnigricans is presented.A comprehensive review of literature with a deductive clinical comparison of the two paraneoplastic syndromes is highlighted.