Effects Of Biologics Treatment In Type 2-High Chronic Rhinosinusitis With Nasal Polyp Patients.

Sharon Van Nevel,Tim Meese,Gabriele Holtappels,Natalie De Ruyck,Stijn Vanhee,Nan Zhang,Filip Van Nieuwerburgh,Claus Bachert

Journal of Allergy and Clinical Immunology（2023）

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摘要

Chronic rhinosinusitis with nasal polyps (CRSwNP) is often characterized by a type 2 inflammation of nasal and sinus mucosa, frequently with comorbid asthma. Development of immunomodulatory drugs, targeting these inflammatory pathways, advanced treatment methods. We aimed to investigate how different biologicals modulate inflammation and understanding different responder rates in distinct patient populations.

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nasal polyp patients,biologics treatment

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