A New Drimane Sesquiterpene Ester from the Marine-Derived Fungus Penicillium chrysogenum LD-201810

Qingrong Huang,Yanhua Wang,Xiaoyan Chi,Chong Liu,Jianlong Zhang

Chemistry of Natural Compounds（2022）

Cited 1|Views7

No score

Abstract

Chrysoride A ( 1 ), a new natural product belonging to the family of drimane sesquiterpene esters, was isolated from a marine-derived fungus Penicillium chrysogenum LD-201810. Its structure was established by detailed interpretation of 1D ( 1 H and 13 C) NMR, 2D ( 1 H– 1 H COSY, HSQC, HMBC, and NOESY) NMR, and HR-ESI-MS data. Chrysoride A ( 1 ) exhibited moderate cytotoxicity against HepG2 and HeLa cancer cell lines with IC 50 values of 28.9 and 35.6 μM, respectively.

Translated text

Key words

drimane sesquiterpene ester,Penicillium chrysogenum,secondary metabolites,cytotoxic activity

AI Read Science

Must-Reading Tree

Example

Generate MRT to find the research sequence of this paper

Chat Paper

Summary is being generated by the instructions you defined