Heterogeneity of CD4+ T cell subsets in EoE drives inflammation and B cell help

Daniel Lozano-Ojalvo,Cecilia Berin,David Dunkin,Wajiha Kazmi, David Menchen-Martinez,Xin Chen,Scott Tyler

Journal of Allergy and Clinical Immunology（2023）

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摘要

Eosinophilic esophagitis (EoE) is a Type 2 cytokine-biased inflammation of the esophagus that is triggered by foods. Th2 cells and Tregs have been identified in the esophagus by flow cytometry and single cell RNAseq, however functional characteristics of T cells in EoE remain poorly understood.

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关键词

inflammation,eoe,cd4+,cell

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