Evaluation of a Panel of Cellular Biomarkers for Immune Dysregulation in Inborn Errors of Immunity

Priya Patel, Boglarka Ujhazi, Melis Yilmaz, David Potts, Maryssa Ellison, Cristina Meehan, Sumai Gordon, Rachel Cruz, Irmel Ayala, Don Eslin, Erin Cockrell, Felipe Rico, Jennifer Mayer, Mei Sing-Ong, Anna Meyer, Charles Hauk, Joseph Dasso, Emma Westermann-Clark, Panida Sriaroon, Kriztian Csomos, Jolan Walter

Journal of Allergy and Clinical Immunology（2023）

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摘要

Inborn errors of immunity (IEI) may present with immune dysregulation due to a variety of impairments in tolerance mechanisms. Several lymphocyte subsets have been proposed as biomarkers for immune dysregulation, but their importance in pathomechanisms and monitoring disease activity is unclear.

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关键词

immune dysregulation,cellular biomarkers,immunity,inborn errors

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