Chiral derivatization-enabled discrimination and on-tissue detection of proteinogenic amino acids by ion mobility mass spectrometry

Chengyi Xie,Yanyan Chen,Xiaoxiao Wang,Yuanyuan Song,Yuting Shen,Xin Diao,Lin Zhu,Jianing Wang,Zongwei Cai

Chemical Science（2022）

引用 7|浏览5

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摘要

The combination of chiral derivatization and ion mobility-mass spectrometry provides the first insights into the separation of 19 pairs of chiral proteinogenic d/l-amino acids in a single run and detection of chiral amino acids in complex samples.

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关键词

proteinogenic amino acids,mass spectrometry,derivatization-enabled,on-tissue

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