Real-World HbF Status in Sickle Cell Disease from an Endemic Zone

Introduction: Sickle cell disease is debilitating hereditary disorder affecting large tribal population in certain parts of India. Complications of sickle cell disease are veno-occlusive crisis, gall stones, leg ulcers, stroke, anemia requiring transfusions adding to the decreasing quality of life. Usage of hydroxyurea increase value of HbF and thereby decreases the complications. To assess the real world scenario of SCD patients, particularly, there levels of HbF, a random clinical examination with blood sampling was initiated and compared to baseline available data.