Research progress of long non-coding RNA in ovarian cancer: a narrative review

Background and Objective: Ovarian cancer (OC) is one of the most lethal malignancies of women around the world. Among all gynecological malignant tumours, most OC patients are diagnosed at advanced stages with a low 5-year survival rate and dim prognosis. Long non-coding RNAs (lncRNAs) are a class of noncoding RNA over 200 nucleotides without protein coding capacity. LncRNAs are involved in different biological processes and form various regulatory networks in different type of cancers. Their aberrant expression plays an important role in the neoplasm and development of OC.