I₂-mediated coupling of quinazolinone enamines with 2-aminopyridines: a new strategy to access spiroquinazolinones

Jingxi Fang,Zhentao Pan, Tong Liu, Yingbo Rao, Huajiang Jiang,Yongmin Ma

Organic & Biomolecular Chemistry（2023）

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摘要

A novel metal-free and mild strategy for the construction of spiroquinazolinone iodides and imidazo[1,2-a]pyridine via an umpolung strategy mediated by molecular iodine is described.

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quinazolinone enamines

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I2-mediated coupling of quinazolinone enamines with 2-aminopyridines: a new strategy to access spiroquinazolinones

I₂-mediated coupling of quinazolinone enamines with 2-aminopyridines: a new strategy to access spiroquinazolinones