An integrative literature review on the SARS-CoV-2 virus from 2015 to 2022
Brazilian Journal of Health Review(2023)
摘要
Coronaviruses of the order Nidovirales and families Coronaviridae, Arteriviridae, Mesoniviridae, Roniviridae were first isolated in 1937 and described in 1965. In 2019, the SARS-CoV-2 coronavirus was responsible for the coronavirus disease in 2019 (COVID-19) in Worldwide. Due to the great importance of SARS-CoV-2, this study integrated information about the virus, as a response: its origin, diagnosis and treatment, diagnosis and treatment. For this, a bibliographic survey was carried out in the Scielo, PubMed and Google Scholar databases regarding SARS-CoV-2, in order to describe its characteristics. SARS-CoV-2 does not yet have a well-clarified pathophysiology, it is known that it can cause an acute or chronic lung injury and that this condition resembles SARS-CoV, which results in aggressive inflammation initiated by viral replication. Both SARS-CoV and SARS-CoV-2 replicated similarly in alveolar epithelium, but SARS-CoV-2 replicates extensively in bronchial epithelium. Reverse transcription followed by polymerase chain reaction (RT-PCR) is widely used to identify viruses that cause respiratory secretions. Currently, with an ongoing viral pandemic, the importance of identifying the pathophysiological characteristics of SARS-CoV-2 and its serious impact on global public health becomes increasingly evident, especially with regard to the remarkable overload of health services, both private and public.
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sars-cov
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