312P ClinMatch: A clinical trial matching platform that improves trial accessibility among NSCLC patients through comprehensive genomic and clinical profiling

A.C.S. Yu, A.K-Y. Yim, S.F. Nyaw, K.K-M. Li,Y.M. Lau, S.C.M. Li, S.T.F. Mok, G. Tang, A. Chang, V. Prêtre, N. Jin, A.K.L. Kai, T.C.M. Kan, H.C. Lee,T.F. Chan, C.S-C. Wong, W.C.S. Cho, H.H.F. Loong

Annals of Oncology(2022)

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摘要
Comprehensive genomic profiling (CGP) has become the cornerstone of personalised oncology treatment. Therapeutic approaches based distinctively to patients’ demographics, prior treatment and genomic profiles are now being investigated in clinical trials. Access to suitable trials have also shown to improve outcome. Current trial subject recruitment process is hampered by manual examination of eligibility criteria. An automated decision support system coupled with CGP may help increase clinical trials recruitment and reduce screen failure rates.
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