236P Chrono-chemotherapy combined with radiotherapy for locally advanced nasopharyngeal carcinoma: A meta-analysis

Nasopharyngeal carcinoma is a disease unique to Southeast Asia. Radiotherapy and chemotherapy serve as the standard treatment mode for locally advanced nasopharyngeal carcinoma (LANPC), but the efficacy is not ideal due to local recurrence and distant metastasis. Meanwhile, studies have shown concurrent chemoradiotherapy will aggravate treatment-related side effects. Chrono-chemotherapy is to select the appropriate timing of administration according to the biological rhythm of the human body, in order to improve the efficacy and reduce side effects.