Recent progress in innate neuro-immunology holds great promises for the management of inflammatory diseases

Nervous and immune systems are devoted to threat identification and are essential for host survival (Fig. 1A). In this commentary, we shed light on papers that experimentally dissected the cross-talk between the nervous and the innate immune systems, using animal models and clinical trials. Next, we emphasize data showing how meditation can enable a control of the inflammatory status and provide some recent examples of high throughput genome-wide research that set the grounds for the elucidation of the immune/mind connections at the molecular level.