Eight clusters of long-covid symptoms

Introduction: Symptoms after covid are common. The clinical manifestation of long-covid was9t described completely for the long term period. Aim: The aim was to describe veariety of patient9s symptoms at least 4months after infection. Methods: a)prepare questionnaire items;b)selection of relevant items;c)formal adjustment;d)pilot verification on 50pts;e)modification of the structure of questions;f)performing an exploratory factor analysis. Results: We enrolled 703consecutive pts(352 males;53±15yrs;BMI 29±5;222±112days from diagnosis)from Mar21 to Jan22. Two-fifths(272pts;39%)of them were initialy hospitalized due to covid. Eight clusters of long-covid symptoms/manifestations(s/m)were identified: respiratory+fatigue cluster;musculo-skeletal c.;skin c.;psychical c.;recurrent infections c.;smell+taste c.;trombotic c;nefrological c.Elderly pts were more affected by musculoskeletal s/m;less frequently experienced psychical s/m;recurrent infection s/m;small+taste s/m.Obese pts reported more frequently respiratory+fatigue s/m;musculo-skeletal s/m; thrombotic s/m;nephrological s/m. Educational level was not associated with the dominance of any s/m cluster. The Delta variant predisposed to the dominance of respiratory+fatigue s/m;musculo-skeletal s/m. Previously hospitalized suffered more frequently from musculo-skeletal s/m;trombotic s/m;less frequently from smell+taste s/m. Conclusion: Manifestation of long-covid symptoms is heterogeneous condition for many months after the initial diagnosis.