RWD83 Real-World Treatment Patterns in Chronic Spontaneous Urticaria in the United States

Treatment of chronic spontaneous urticaria (CSU) in the US is a stepwise approach recommended by local guidelines. First line: non-sedating H1-antihistamines (ns-H1AH); 2nd line & 3rd line: increased licensed dose ns-H1AH or change of H1AH or add H2-antihistamines (H2AH) or leukotriene inhibitor (LTRA) or sedating H1AH or doxepin; 4th line: add omalizumab or cyclosporine. Rescue medication with short-course oral corticosteroids (OCS), in case of exacerbations. The objective of the study was to assess real-world treatment patterns in adult patients with CSU.