Carbon nanotubes activate inflammatory signalling through binding to Siglec-14

Nature Nanotechnology（2023）

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摘要

Discovery of a novel axis through which multi-walled carbon nanotubes (MWCNTs) elicit toxicity in human macrophages, involving the propagation of inflammatory signalling via the Siglec-14-DAP12-Syk pathway, and how it may be controlled pharmacologically.

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关键词

inflammatory,carbon

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