A spiral microfluidic chip endows high efficiency single cell alignment at extremely low flow for ICP-MS analysis
Microchemical Journal(2023)
Abstract
•A spiral microfluidic chip was designed to achieve cells focusing and sorting at low flow rate.•The focusing capability of the chip was demonstrated by fluorescent particles and MCF-7 cells.•The uptake of [Co(tpa)(cur)](ClO4)2 by individual cells was investigated with detection of TRA-ICP-MS.
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Key words
ICP-MS,Microfluidics,Low flow rate,Single cell analysis
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