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A spiral microfluidic chip endows high efficiency single cell alignment at extremely low flow for ICP-MS analysis

Xing Wei,Yu-Jia Wei,Xuan Zhang, Cheng-Xing Wu,Ming-Li Chen, Jian-Hua Wang

Microchemical Journal(2023)

Cited 1|Views16
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Abstract
•A spiral microfluidic chip was designed to achieve cells focusing and sorting at low flow rate.•The focusing capability of the chip was demonstrated by fluorescent particles and MCF-7 cells.•The uptake of [Co(tpa)(cur)](ClO4)2 by individual cells was investigated with detection of TRA-ICP-MS.
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Key words
ICP-MS,Microfluidics,Low flow rate,Single cell analysis
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