Bone marrow Ki‐67 index is of prognostic value in newly diagnosed multiple myeloma

Shebli Atrash,Myra Robinson,Alankrita Taneja,Barry Paul,Kristen Cassetta,Ami Ndiaye,Cindy Varga,Jared Block,Edward H. Lipford,Elton T. Smith,Chad M. McCall,Virginia Thurston,David Foureau,Saad Z. Usmani,Peter M. Voorhees,Manisha Bhutani

European Journal of Haematology（2023）

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摘要

Our results demonstrate that a high Ki-67 index (>5%) is an independent prognostic marker associated with worse OS and PFS in newly diagnosed MM. IHC staining for Ki-67 on bone marrow biopsies could be easily adopted as a prognostic biomarker for MM in economically constrained healthcare settings.

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关键词

biomarker, Ki-67, newly diagnosed multiple myeloma, prognosis

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