Neutrophil-Related Gene Expression Signatures in Idiopathic Pulmonary Fibrosis: Implications for Disease Characteristic and Identification of Diagnostic Hub Genes

Yingying Lin,Xiaofan Lai, Tianxiang Lei,Yuan Qiu,Qiwen Deng,Qi Liu,Zhongxing Wang,Wenqi Huang

Journal of Inflammation Research（2023）

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摘要

Our findings provide evidence of a low neutrophil-infiltrating characteristic in the IPF microenvironment and identify hub genes related to neutrophils that may serve as diagnostic biomarkers for the disease.

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关键词

neutrophils, idiopathic pulmonary fibrosis, immune infiltration analysis, weighted gene co-expression network analysis, consensus cluster analysis, diagnostic model, biomarkers

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