Phytochemical constituents from the rhizomes of Kaempferia parviflora Wall. ex Baker and their acetylcholinesterase inhibitory activity
NATURAL PRODUCT RESEARCH(2024)
Abstract
Phytochemical study on the rhizomes of Kaempferia parviflora led to the isolation of twenty-three compounds including six phenolic glycosides (1-6), thirteen flavones (7-19), and five phenolic compounds (20-23). Of these, the new compounds were determined to be 2,4-dihydroxy-6-methoxyacetophenone-2-beta-D-apiofuranosyl-(1 -> 6)-beta-D-glucopyranoside (1), 2-hydroxy-4-propionyl-phenyl O-beta-D-glucopyranoside (2), and 4-hydroxy-3,5-dimethoxyacetophenone 8-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-D-glucopyranoside (3) and named as kaempanosides A-C, respectively. Their chemical structures were established based on HR-ESI-MS, 1D and 2D NMR spectra. All compounds 1-23 exhibited acetylcholinesterase inhibitory activity with IC50 values ranging from 57.76 to 253.31 mu M.
MoreTranslated text
Key words
Kaempferia parviflora,Zingiberaceae,kaempanoside A,kaempanoside B,kaempanoside C,acetylcholinesterase inhibitory activity
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined