Martin Silicates as Versatile Radical Precursors in Photoredox/Nickel Dual Catalysis (Apr, 10.1055/a-2059-3498, 2023)

A cross-coupling methodology is described based on the nickel-catalyzed connection of an aryl moiety to an alkyl radical generated by photoinduced single-electron oxidation of a silicate formed from a Martin spirosilane. Complementary to the other anionic radical precursors in photoredox catalysis, Martin silicates permit access to highly reactive alkyl radicals directly engageable in smooth C(sp(2))- C(sp(3)) bond-formation reactions.