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Anaphylactic Reaction to Cryoprecipitate in a Patient with Von Willebrand Disease During Factor Correction for Elective Cesarean Section

Samanka Bandara, Maduka Imali, Madura Wanasinghe,Chathura Ratnayake,Vasanthi Pinto, Padmalal Desilva

SRI LANKAN JOURNAL OF ANAESTHESIOLOGY（2023）

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Abstract
A 40-year-old patient with Type I Von Willebrand Disease presented for elective cesarean section. At the operating theater before delivery, while receiving cryoprecipitate, she developed an anaphylactic reaction requiring resuscitation. Once she was hemodynamically stable, factor VIII/VWF concentrates were administered and operative delivery performed, with a good maternal and fetal outcome.
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Key Words, Von Willebrand disease, cesarean section, cryoprecipitate, anaphylactic reaction, B-Lynch suture
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