Assessment of the protective effect against air pollution-induced skin pigmentation of an oral nutritional supplement containing antioxidants: A randomized, double-blinded, placebo-controlled study

A. Marini, N. Aue, T. Jaenicke,S. Grether-Beck,C. Trullas,C. Granger, E. Jourdan,J. Krutmann

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY(2023)

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Journal of the European Academy of Dermatology and VenereologyEarly View LETTER TO THE EDITOR Assessment of the protective effect against air pollution-induced skin pigmentation of an oral nutritional supplement containing antioxidants: A randomized, double-blinded, placebo-controlled study A. Marini, A. Marini orcid.org/0000-0002-9911-5793 IUF – Leibniz Research Institute of Environmental Medicine, Düsseldorf, GermanySearch for more papers by this authorN. Aue, N. Aue IUF – Leibniz Research Institute of Environmental Medicine, Düsseldorf, GermanySearch for more papers by this authorT. Jaenicke, T. Jaenicke IUF – Leibniz Research Institute of Environmental Medicine, Düsseldorf, GermanySearch for more papers by this authorS. Grether-Beck, S. Grether-Beck orcid.org/0000-0002-8318-2625 IUF – Leibniz Research Institute of Environmental Medicine, Düsseldorf, GermanySearch for more papers by this authorC. Trullas, C. Trullas ISDIN S.A, Barcelona, SpainSearch for more papers by this authorC. Granger, C. Granger Stella Polaris Europe, Paris, FranceSearch for more papers by this authorE. Jourdan, E. Jourdan ISDIN S.A, Barcelona, SpainSearch for more papers by this authorJ. Krutmann, Corresponding Author J. Krutmann [email protected] orcid.org/0000-0001-8433-1517 IUF – Leibniz Research Institute of Environmental Medicine, Düsseldorf, Germany Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany Correspondence J. Krutmann, IUF – Leibniz Research Institute of Environmental Medicine, Düsseldorf, Germany. Email: [email protected]Search for more papers by this author A. Marini, A. Marini orcid.org/0000-0002-9911-5793 IUF – Leibniz Research Institute of Environmental Medicine, Düsseldorf, GermanySearch for more papers by this authorN. Aue, N. Aue IUF – Leibniz Research Institute of Environmental Medicine, Düsseldorf, GermanySearch for more papers by this authorT. Jaenicke, T. Jaenicke IUF – Leibniz Research Institute of Environmental Medicine, Düsseldorf, GermanySearch for more papers by this authorS. Grether-Beck, S. Grether-Beck orcid.org/0000-0002-8318-2625 IUF – Leibniz Research Institute of Environmental Medicine, Düsseldorf, GermanySearch for more papers by this authorC. Trullas, C. Trullas ISDIN S.A, Barcelona, SpainSearch for more papers by this authorC. Granger, C. Granger Stella Polaris Europe, Paris, FranceSearch for more papers by this authorE. Jourdan, E. Jourdan ISDIN S.A, Barcelona, SpainSearch for more papers by this authorJ. Krutmann, Corresponding Author J. Krutmann [email protected] orcid.org/0000-0001-8433-1517 IUF – Leibniz Research Institute of Environmental Medicine, Düsseldorf, Germany Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany Correspondence J. Krutmann, IUF – Leibniz Research Institute of Environmental Medicine, Düsseldorf, Germany. Email: [email protected]Search for more papers by this author First published: 12 May 2023 https://doi.org/10.1111/jdv.19183Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL REFERENCES 1Vierkotter A, Schikowski T, Ranft U, Sugiri D, Matsui M, Kramer U, et al. Airborne particle exposure and extrinsic skin aging. J Invest Dermatol. 2010; 130: 2719– 26. 2Grether-Beck S, Felsner I, Brenden H, Marini A, Jaenicke T, Aue N, et al. Air pollution-induced tanning of human skin. Br J Dermatol. 2021; 185: 1026– 34. 3Baswan SM, Klosner AE, Weir C, Salter-Venzon D, Gellenbeck KW, Leverett J, et al. Role of ingestible carotenoids in skin protection: a review of clinical evidence. Photodermatol Photoimmunol Photomed. 2021; 37: 490– 504. 4Baswan SM, Marini A, Klosner AE, Jaenicke T, Leverett J, Murray M, et al. Orally administered mixed carotenoids protect human skin against ultraviolet A-induced skin pigmentation: a double-blind, placebo-controlled, randomized clinical trial. Photodermatol Photoimmunol Photomed. 2020; 36: 219– 25. 5Kopcke W, Krutmann J. Protection from sunburn with beta-Carotene–a meta-analysis. Photochem Photobiol. 2008; 84: 284– 8. 6Granger C, Aladren S, Delgado J, Garre A, Trullas C, Gilaberte Y. Prospective evaluation of the efficacy of a food supplement in increasing Photoprotection and improving selective markers related to skin photo-ageing. Dermatol Ther (Heidelb). 2020; 10: 163– 78. 7Kowalska K, Milnerowicz H. The influence of age and gender on the pro/antioxidant status in young healthy people. Ann Clin Lab Sci. 2016; 46: 480– 8. 8Pinchuk I, Weber D, Kochlik B, Stuetz W, Toussaint O, Debacq-Chainiaux F, et al. Gender- and age-dependencies of oxidative stress, as detected based on the steady state concentrations of different biomarkers in the MARK-AGE study. Redox Biol. 2019; 24:101204. 9Burkholder S, Jilcott Pitts S, Wu Q, Bayles J, Baybutt R, Stage VC. Skin carotenoid status over time and differences by age and sex among head start children (3-5 years). J Nutr Educ Behav. 2021; 53: 103– 9. Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation
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skin pigmentation,antioxidants,air pollution‐induced,oral nutritional supplement
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