Application of two-dimensional speckle tracking imaging in the follow-up of patients with coronary heart disease treated with metalol

Mengyuan Li, Chunwang Zhou,Li Li, Yi Ma,Biqiong Zhao

TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH(2023)

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摘要
Purpose: To investigate the application of two-dimensional speckle tracking imaging (2D-STI) in the follow-up of patients with coronary heart disease (CHD) who were treated with metalol.Methods: A total of 100 patients with CHD (CHD group) who were treated with metalol and had undergone percutaneous coronary intervention (PCI) at Tangshan Works' Hospital, Tangshan, China, and another 100 healthy people (control group) were enrolled in this study. Prior to and after 6 months of treatment, echocardiography was performed on patients in control and CHD groups, respectively, and the wall motion score was calculated. The 2D-STI was used to obtain systolic peak longitudinal strain value (SLs), global peak longitudinal strain (GSL) and early diastolic peak longitudinal strain rate (SrLe) in the early diastolic period of 6 wall basal segments, middle segments, and apical segments of the left ventricle.Results: The wall motion score index (WMSI) of CHD group was higher than that of the control group, while the WMSI of CHD group after treatment was significantly lower than the value before treatment, (p < 0.05). In 2D-STI, the SLs, SrLe and GLS of patients after 6 months of treatment were significantly higher than those before treatment (p < 0.05).Conclusion: Thus, 2D-STI can be used to quantify the motion of the chamber wall and the effect of PCI surgery, and it also provides a stable new index and technique for evaluating the effects of treatment of CHD.
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