The Mitochondrial Pyruvate Carrier Coupling Glycolysis and the Tricarboxylic Acid Cycle Is Required for the Asexual Reproduction of Toxoplasma gondii

Congcong Lyu,Yukun Chen, Yanan Meng,Jichao Yang,Shu Ye,Zhipeng Niu, Issam EI-Debs,Nishith Gupta,Bang Shen

Microbiology Spectrum（2023）

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摘要

T. gondii is a zoonotic parasite capable of infecting many warm-blooded organisms, including humans. Among others, a feature that allows it to parasitize multiple hosts is its exceptional metabolic plasticity.

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