Modulation of Cellular Aging in the Drosophila Hematopoietic Organ Alters the Cell Lineage Trajectories and Blood Cell Homeostasis

Background: Organismal aging is accompanied by a progressive decline in cellular and molecular functioning affecting organismal health and longevity. Stem cell aging is a hallmark of aging that results in disruption of normal functioning of organs. Our current study investigates the effect of aging on the hematopoietic system using Drosophila.