Frontal QRS-T Angle and Fragmented QRS in Bipolar Disorder, Do They Differ From The Healthy Subjects?

Objective: It is important to assess the likelihood of cardiovascular disease in patients with bipolar disorder (BD). According to the literature, frontal QRS-T may be a cardiovascular disease indicator. Material and Method: In the present investigation, we studied the demographic details, electrocardiogram (ECG) variables, and blood test results of 90 healthy controls (HC) and 97 patients we followed for BD diagnosis. Results: Age and gender trends were similar between the BD and HC groups (p=0.844 and p=0.664). BD had a higher mean number of fragmented QRS (fQRS) than the HC group, and fQRS was more frequent (p=0.002 and p=0.007). The frontal QRS-T angle was wider in the BD group than it was in the HC group (p=0.038). Monocyte-to-lymphocyte ratio (MLR), monocytes to high-density lipoprotein cholesterol (HDL-C) ratio (MHR), and atherogenic index of plasma (AIP) were statistically greater in BD patients (p=0.021, p