The cancer of the bladder risk assessment (cobra) score and mortality-survival relationship in patients who have undergone radical cystectomy in the turkish urooncology association database

You have accessJournal of UrologyCME1 Apr 2023MP32-10 THE CANCER OF THE BLADDER RISK ASSESSMENT (COBRA) SCORE AND MORTALITY-SURVIVAL RELATIONSHIP IN PATIENTS WHO HAVE UNDERGONE RADICAL CYSTECTOMY IN THE TURKISH UROONCOLOGY ASSOCIATION DATABASE Hasan Tavukçu, Ilker Tinay, Volkan Izol, Sümer Baltaci, Kerem Teke, Evren Süer, Uğur Yücetaş, Sertaç Yazici, Serkan Akan, Bahadir Şahin, and Members Of Urooncology Hasan TavukçuHasan Tavukçu More articles by this author , Ilker TinayIlker Tinay More articles by this author , Volkan IzolVolkan Izol More articles by this author , Sümer BaltaciSümer Baltaci More articles by this author , Kerem TekeKerem Teke More articles by this author , Evren SüerEvren Süer More articles by this author , Uğur YücetaşUğur Yücetaş More articles by this author , Sertaç YaziciSertaç Yazici More articles by this author , Serkan AkanSerkan Akan More articles by this author , Bahadir ŞahinBahadir Şahin More articles by this author , and Members Of UrooncologyMembers Of Urooncology More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003265.10AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The Cancer of the Bladder Risk Assessment (COBRA) Score is observed as a practical and useful method that can be used to predict survival in patients who have undergone radical cystectomy. We also aimed to evaluate survival by using COBRA score in the bladder cancer patient group in our country. METHODS: A total of 910 patients who had undergone radical cystectomy were included in the Turkish Urooncology Association database. Patients were classified according to tumor stage and lymph node (TLN) involvement; Mortality rates and survival were analyzed according to both TLN classification and COBRA score. RESULTS: The mean age of the patients was 63.94±9.55 years, of which 450 (49.5%) were male and 460 (50.5%) were female; while 279 (30.7%) had lymph node involvement, 631 (69.3%) did not. Cancer specific mortality and overall mortality rates were found to be significantly higher in patients with lymph node involvement (p:0.000*, p:0.042*). There is a statistically significant difference between the COBRA scores and the survival rates in terms of cancer specific mortality according to TLN classification (p:0.000; p<0.05). Survival rate of group with pathological T3-T4 Node (+) were significantly lower than the other groups (p<0.05). Survival rate of group with 更多