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Systematic Analysis of Metabolic Bottlenecks in the Methylerythritol 4-Phosphate (MEP) Pathway of Zymomonas mobilis

Daven B. Khana,Mehmet Tatli,Julio Rivera Vazquez,Sarathi M. Weraduwage,Noah Stern,Alexander S. Hebert,Edna Angelica Trujillo,David M. Stevenson,Joshua J. Coon,Thomas D. Sharky,Daniel Amador-Noguez

mSystems（2023）

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Abstract
Engineered microorganisms have the potential to convert renewable substrates into biofuels and valuable bioproducts, which offers an environmentally sustainable alternative to fossil-fuel-derived products. Isoprenoids are a diverse class of biologically derived compounds that have commercial applications as various commodity chemicals, including biofuels and biofuel precursor molecules.
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