Supplementary Data from Circulating Proteoglycan Endocan Mediates EGFR-Driven Progression of Non–Small Cell Lung Cancer

crossref(2023)

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SUPPLEMENTARY INFORMATION Supplementary material and methods, Table S1, and Figure S1-S7 - This file contains Supplementary material and methods; Table S1. The Cox univariate and multivariate analyses of endocan and clinicopathological factors in overall survival of patients in NSCLC patients.; Supplementary Figure S1. The clinical value of endocan in lung adenocarcinoma.; Supplementary Figure S2. Correlation of endocan and EGFR expression in lung cancer patients.; Supplementary Figure S3. Endocan enhances EGF�induced activation of EGFR in a concentration-dependent manner.; Supplementary Figure S4. The JAK/STAT3 and ERK/ELK signaling regulates endocan promoter activity.; Supplementary Figure S5. The interaction of endocan and EGF/EGFR complex.; Supplementary Figure S6. Endocan peptide treatment inhibits the PC9 tumor growth in vivo.; Supplementary Figure S7. Endocan peptide treatment suppresses the activation of EGFR harboring L858R/T790M/C797S triple mutations.

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