Supplementary Figures 1 through 5, Supplementary Figures 8 and 9, and Supplementary Figure Legends from Copy Number Alterations in Enzyme-Coding and Cancer-Causing Genes Reprogram Tumor Metabolism

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Abstract

Fig. 1 - Description of genomic datasets, list of cancer causing genes and metabolic genes used in this study. Fig. 2 - The distribution of cancer causing genes, metabolic genes and the corresponding gene pairs in the genome. Fig. 3 - The distribution of RnpMI scores across all cancer types. Fig. 4 - Correlation between RnpMI scores and co-occurrence frequency. Fig. 5 - Gene counts after the iMetCG prioritization steps. Fig. 6 - (see additional file Supp. Fig. 6). Heatmap of prioritized cancer metabolic gene set. Fig. 7 - (see additional file Supp. Fig. 7). Heatmap of core metabolic gene set. Fig. 8 - Co-alteration of proximal cancer-metabolic gene pairs across tumor types. Fig. 9 - Tumor classification.

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