Supplementary Figures 1-13 from The SWI/SNF Complex Protein Snr1 Is a Tumor Suppressor in <i>Drosophila</i> Imaginal Tissues

Supplementary figure 1: Snr1 is required for cell survival in Drosophila wing imaginal disc. Supplementary figure 2: Tumorigenic overgrowth in wing discs carrying snr1-depletion by tissue-specific Gal4 drivers. Supplementary figure 3: Coexpression of rpr and p35 does not induce neoplastic tumorigenic overgrowth in the wing disc. Supplementary figure 4: Wing discs with snr1 loss shows neoplastic overgrowth. Supplementary figure 5: Tumorigenic overgrowth in the wing disc with mosaic clones of snr1 mutation. Supplementary figure 6: Depletion of brm or osa causes apoptotic phenotype in wing pouch region. Supplementary figure 7: Subcellular localization in salivary gland cells. Supplementary figure 8: Knockdown of other components of the SWI/SNF complex does not affect trafficking signaling. Supplementary figure 9: Transmembrane proteins are not accumulated in brm- or osa-depleted cells. Supplementary figure 10: Notch signaling is not upregulated in brm- or osa-RNAi cells. Supplementary figure 11: Depletion of brm or osa does not change JAK-STAT signaling activity. Supplementary figure 12: JNK signaling is barely affected in brm- or osa-depleted cells. Supplementary figure 13: Knockdown of dilp8 or mmp1 does not suppress snr1 depletion-induced tumorigenic overgrowth.