Figure S5 from The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State

Jae Hyuk Yoo,Samuel W. Brady, Lehi Acosta-Alvarez,Aaron Rogers,Jingfu Peng,Lise K. Sorensen, Roger K. Wolff, Tara Mleynek,Donghan Shin, Coulson P. Rich,David A. Kircher,Andrea Bild,Shannon J. Odelberg,Dean Y. Li,Sheri L. Holmen,Allie H. Grossmann

crossref（2023）

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Abstract

Figure S5: ARF6-GTP induces morphologic changes in mouse melanoma cells. Bright field images (100x magnification) of primary mouse melanoma cell lines derived from control BrafCA;Cdkn2af/f (5588) or BrafCA;Cdkn2af/f + Arf6Q67L (6431, 6455) mice. ARF6-GTP induces elongation/spindling of tumor cells relative to the more polygonal-shaped controls. Scale bars = 400um.

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