Supplementary Figure 7 from Increased Survival of Glioblastoma Patients Who Respond to Antiangiogenic Therapy with Elevated Blood Perfusion

PDF file - 382K, Figure S7: Relationship Between Increased Microvessel Flow and Metabolic Status of Tumors. Averaged changes in MRS ratios for patients with an increase in microvessel flow (n=5; 2 patients did not have MRS data). Relative to pretreatment values, metabolic ratios for NAA/norCre were significantly higher at days +28, +56 and at day +28 for Cho/norCre (*Wilcoxon signed-rank; P<0.05). After day +56, the observed anti-tumor response was reversed. Numerical data show log-scaled averaged values (�SEM) and values at day -1 were set as 100% in all lesions.