Supplementary Data from Phosphorylation of SOCS1 Inhibits the SOCS1–p53 Tumor Suppressor Axis

Supplementary data contains additional methods and reagents and figures. The figures contain the following information: Supplementary Figure 1 extends figure 1 providing evidence that SOCS1 may interact with hydrophobic motifs present in many transcription factors. Supplementary Figure 2 supports figure 1 showing SOCS1 mutations found in human cancers that affect the SOCS1-p53 interacting motif Supplementary Figure 3 extends figures 1 and 2 providing additional functional characterization of SOCS1 mutants that affect p53 binding. Supplementary Figure 4 supports figure 5 showing SOCS1, p53, and YES1 expression levels in DLBCL. Supplementary Figure 5 supports figure 5 showing a description of patients' samples using to study phospho-SOCS1 levels by cancer subtype and different kinds of phospho-SOCS1 staining in these samples. Supplementary figure 6 supports figure 6 showing SRC family expression in DLBCL according to Oncomine. Supplementary Figure 7 supports figure 6 showing controls for the PLA that shows SOCS1-p53 interaction.