Supplementary Figures S1-S5 from CHK1 Inhibition Synergizes with Gemcitabine Initially by Destabilizing the DNA Replication Apparatus

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Supplementary Figures S1-S5. Effective synergy at sub-GI50 concentrations (S1); Mitotic entry at synergistic concentrations (S2); Cell fate upon gemcitabine and CHK1 inhibition (S3); Replication stress upon gemcitabine and CHK1 inhibition (S4); Mitotic aberration upon gemcitabine and CHK1 inhibition (S5).

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