Supplementary Figures S1-2, Tables 1-2 from Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53

Supplementary Figures S1-2, Tables 1-2 Supplementary figure S1. Cell cycle profiles of cancer cells at 8 hours after NSC59984 treatment. Supplementary Figure S2. Effect of NSC59984 treatment on the conformation of mutant p53 in cancer cells. Supplementary Table 1. Combination indices for the NSC59984 treatment with Ad-p73 on cell viability in DLD-1 cells. Supplementary Table 2. Combination indices for the NSC59984 and CPT-11 treatment on cell viability in cells.