Supplemental Figures and Tables from Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia

Supplemental Figure 1 (SF1) describes lifespan in global PTP1B-/- mice. SF2 shows development of leukemia is associated with myeloid PTP1B complete deficiency. SF3 shows tumors in LysM PTP1B-/- mice. SF4 presents LysM PTP1B-/- microarray data. SF5 presents STAT5 expression data. SF6 presents additional STAT3 ChIP seq data from LysM PTP1B mice. Tables 1-4 demonstrate detailed statistics for survival data on LysM PTP1B and global PTP1B-/- mice as well as hepatic pre-tumour microarray data from LysM PTP1B-/- and control mice.