Supplementary Figures from Distinct Interactions of EBP1 Isoforms with FBXW7 Elicits Different Functions in Cancer

crossref(2023)

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Abstract

This part describes further supportive information for the distinctive interactions of EBP1 isoforms with FBXW7 including the data to describe that FBXW7-mediated ubiquitination and degradation of EBP1 P48 in a GSK3β-dependent manner and to illustrate that FBXW7 binds to P48 through its WD domain and P48 S44 is crucial for its interaction with FBXW7.

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