Supplementary Figures from Distinct Interactions of EBP1 Isoforms with FBXW7 Elicits Different Functions in Cancer

This part describes further supportive information for the distinctive interactions of EBP1 isoforms with FBXW7 including the data to describe that FBXW7-mediated ubiquitination and degradation of EBP1 P48 in a GSK3β-dependent manner and to illustrate that FBXW7 binds to P48 through its WD domain and P48 S44 is crucial for its interaction with FBXW7.