Case report: Bilateral double beta peak activity is influenced by stimulation, levodopa concentrations, and motor tasks, in a Parkinson's disease patient on chronic deep brain stimulation.

Giulia Giannini,Luca Baldelli, Gaetano Leogrande,Ilaria Cani,Paolo Mantovani,Giovanna Lopane,Pietro Cortelli,Giovanna Calandra-Buonaura,Alfredo Conti

Frontiers in Neurology（2023）

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Abstract

This single exploratory case study illustrates a complex behavior of low-and high-beta peaks in a PD patient, in response to stimulation, L-dopa plasma levels, and motor performances. Our results suggest the importance to investigate patient-specific individual LFP patterns in view of upcoming closed-loop stimulation.

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Key words

Parkinson’s disease,deep brain stimulation,local field potentials,beta band frequency,case report

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