Comparison of interleukin-6 levels among dental implants with sandblasted acid etched and anodized surface

Aim: To increase the success of dental implants, numerous surface alterations are performed to them. After implant-tissue contact, inflammation develops as part of the host response. To enhance the function of dental implants, it is crucial to measure the amounts of inflammatory mediators around different surface-treated implants. The purpose of this study was to compare the levels of interleukin-6 (IL-6) among SLA, SLActive and TiUnite implant surfaces.Materials and methods: Subjects with healthy dental implant were categorized into Group 1: SLA (n=25), Group 2: SLActive (n=25), Group 3: TiUnite (n=25). Utilizing an ELISA kit, IL-6 was measured in the peri-implant crevicular fluid (PICF). One-way ANOVA was used for statistical analysis, followed by Tukey's HSD post hoc.Results and discussion: Group 3 had the highest IL-6 level ( 4.39 +/- 0.69 pg/mL), followed by groups 1 (3.22 +/- 0.94 pg/mL) and 2 (1.37 +/- 0.28 pg/mL). The levels of IL-6 varied significantly among the three groups (p = 0.00). Additionally, a statistically significant difference between the groups was revealed by pairwise comparison (p = 0.00).Conclusions: Compared to SLA and SLActive implants, the IL-6 level in the peri-implant crevicular fluid around TiUnite dental implants was higher.