Cadabatone, a New Sesquiterpene Lactone from Cadaba fruticosa

Cadabatone ( 1 ), a new eudesmanolide-type sesquiterpene lactone, has been isolated from the EtOAc soluble subfraction of the methanolic extract of Cadaba fruticosa (L.) Druce, along with known compounds, 3-epierivanin ( 2 ), 3,5,7,4-tetrahydroxyflavone ( 3 ), esculetin ( 4 ), rosmarinic acid ( 5 ), α-amyrin ( 6 ), and β-amyrin ( 7 ), isolated for the first time from this species. The structures of these compounds were elucidated by spectroscopic studies including MS, IR, 1D and 2D NMR spectroscopy.