Association between radiographic findings and knee bone tumors

Background: Bone neoplasms require an adequate clinical-radiographic evaluation for their diagnosis. Plain radiographs are the usual method to establish the diagnosis and evaluate differential diagnoses in the study of bone tumor pathology. Objec-tive: To recognize the frequency of radiographic characteristics and associate them with bone tumor pathology. Method: Radiographic data were collected from 132 patients with tumor pathology confirmed by biopsy from bone tumors service of the Traumatology and Orthopedics Hospital Unidades Medicas de Alta Especialidad Dr. Victorio de la Fuente Narvaez, Insti-tuto Mexicano del Seguro Social, Ciudad de Mexico, during 2019. Results: 132 patients were registered. The most frequent benign tumor was osteochondroma (27.3%), and malignant was osteosarcoma (9.8%). Active lytic lesions (odds ratio [OR]: 6.9; 95% confidence interval [95%CI]: 2.83-16.85) or aggressive (OR: 26.85; 95%CI: 3.21-224) were associated with giant cells tumors. Poorly differentiated intraosseous blast lesions of bone lineage (OR: 36.15; 95%CI: 4.4-295.5) were associated with osteosarcoma. The periosteal reaction (OR: 36.15; 95%CI: 4.4-295.5), the moth-eaten or permeative pattern (OR: 11.75; 95%CI: 1.26-109) and the central location of the lesion (OR: 3.03; 95%CI: 1.37-6.69) were associated with malignant tumor lesions. Conclusions: Poorly defined intraosseous blast lesions of bone lineage, periosteal reaction, and moth-eaten or per-meative pattern of destruction are associated with malignant lesions.