Moderately cold temperatures prevent protein aggregation related to aging and disease

NATURE AGING(2023)

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摘要
Moderately cold temperatures trigger the removal of aggregation-prone proteins in the invertebrate model Caenorhabditis elegans and cultured human cells, preventing the accumulation of pathological aggregates linked with age-related neurodegenerative disorders such as amyotrophic lateral sclerosis and Huntington's disease.
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