A New Eudesmane Sesquiterpenoid from the Marine-Derived Fungus Penicillium sp. HK1-22
CHEMISTRY OF NATURAL COMPOUNDS(2023)
Abstract
new eudesmane-type sesquiterpenoid, artemihedinic acid N ( 1 ), together with four known compounds, aspterric acid ( 2 ), two naphtho- γ -pyrones, peninaphones A ( 3 ) and B ( 4 ), and a diphenyl ether ( 5 ), were isolated from the rice medium fermentations of the mangrove rhizosphere soil-derived fungus Penicillium sp. HK1-22. The structure of 1 was determined by combined spectroscopic methods including 1D and 2D NMR spectral data. The antibacterial activities of all isolated metabolites were evaluated.
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Key words
mangrove rhizosphere soil-derived fungus,Penicillium sp.,sesquiterpenoid,naphtho- γ-pyrones,antibacterial activities
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