Pulmonary carcinoid tumour with remarkably high levels of pro-gastrin-releasing peptide: A case report

An 86-year-old woman presented with chronic cough and chest pain. Computed tomography revealed two masses in the right lower lobe of the lung accompanied by multiple lymphade-nopathies and metastasis to the rib. The pro-gastrin-releasing peptide (ProGRP) levels were notably elevated (888 pg/mL). Based on these findings, our initial clinical diagnosis was small-cell lung cancer. However, the pathological diagnosis turned out to be an atypical carcinoid. The patient was finally treated with everolimus. Clinicians should be aware that carcinoid tu-mours are sometimes difficult to distinguish from small-cell lung cancer with respect to high ProGRP levels and multiple metastases.