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Revealing genetic links of Type 2 diabetes that lead to the development of Alzheimer’s disease

Muhammad Afzal,Khalid Saad Alharbi,Sami I. Alzarea,Najiah M. Alyamani,Imran Kazmi,Emine Güven

HELIYON（2023）

Cited 3|Views21
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Abstract
•The study extracted the most significant genes in common of T2D and AD such as CDKN1A, COL22A1, EIF4A, GFAP, SLC1A1, and VIM.•The hub genes of AD-related genes were validated using network-based methods.•Notional genetics mechanisms of T2D involvement in AD etiology are presented.
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Key words
Alzheimer ?s disease,Type 2 diabetes mellitus,Neovascular unit,Differential expression,Ageing brain
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