One-Pot, Metal-Free Synthesis of Phenols from Arylboronic Acids and Subsequent Conversion with N -Hydroxyphthalimide Esters
SYNTHESIS-STUTTGART(2023)
摘要
A one-pot synthesis of phenyl esters between N-hydroxy-phthalimide (NHP) esters derived from carboxylic acid and arylboronic acids is developed. This tandem reaction underwent mild conditions with a broad range of substrates scope (up to 27 examples) in good to excellent yields (up to 93% yield). The reaction can be easily scaled up, which thus pave the way for further applications in late-stage modification.
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关键词
tandem reactions,metal-free,TBHP,phenol,N -hydroxyphthalimide ester
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