A Review of the Application of Multi-modal Deep Learning in Medicine: Bibliometrics and Future Directions

In recent years, deep learning has been applied in the field of clinical medicine to process large-scale medical images, for large-scale data screening, and in the diagnosis and efficacy evaluation of various major diseases. Multi-modal medical data fusion based on deep learning can effectively extract and integrate characteristic information of different modes, improve clinical applicability in diagnosis and medical evaluation, and provide quantitative analysis, real-time monitoring, and treatment planning. This study investigates the performance of existing multi-modal fusion pre-training algorithms and medical multi-modal fusion methods and compares their key characteristics, such as supported medical data, diseases, target samples, and implementation performance. Additionally, we present the main challenges and goals of the latest trends in multi-modal medical convergence. To provide a clearer perspective on new trends, we also analyzed relevant papers on the Web of Science. We obtain some meaningful results based on the annual development trends, country, institution, and journal-level research, highly cited papers, and research directions. Finally, we perform co-authorship analysis, co-citation analysis, co-occurrence analysis, and bibliographic coupling analysis using the VOSviewer software.