Regional microstructural differences in ADHD youth with and without a family history of bipolar I disorder

Du Lei,Kun Qin,Wenbin Li,Ziyu Zhu,Maxwell J. Tallman,L. Rodrigo Patino,David E. Fleck,Veronica Aghera,Qiyong Gong,John A. Sweeney,Melissa P. DelBello,Robert K. McNamara

Journal of Affective Disorders（2023）

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摘要

Psychostimulant-free ADHD youth with a BD family history exhibit different microstructure alterations in frontal, limbic, and striatal regions compared with ADHD youth without a BD family history, and may therefore represent unique phenotypes relevant to BD risk progression.

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关键词

ADHD, DTI, Bipolar disorder, Limbic system, Fractional anisotropy, Mean diffusivity

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